RESEARCH & DISCOVERIES
The Lab hosts a variety of 3D Printers and Bioprinters, including Fused Deposition Modeling (FDM), Bioprinters (e.g., inkjet, micro extrusion), Photopolymerization Printers (e.g., SLA, DLP, UV LCD), Selective Laser Sintering (SLS), Liquid Deposition Molding, Pellet, Laser, and Food. Including in-house prepared Bio-inks & drug-loaded filaments (using single or twin-screw extruders).
Our studies include: conceptualization, formulation / manufacturing, physicochemical characterization using state-of-the-art techniques, computational modelling, in vivo, ex vivo, and in vitro evaluation.
The research in our Lab consist by a highly qualified research team and cutting-edge technologies.
Examples of current hot-topic research themes / projects, can be found below.
CARDIOVASCULAR DISEASES (CVDS)
Cardiovascular diseases constitute a number of conditions which are the leading cause of death globally. To combat these diseases and improve the quality and duration of life, several cardiac implants can be developed by 3D Printing & Bioprinting, including stents, arterial regeneration, bioresorbable vascular scaffolds, and cardiac patches.
Public engagement is an important and essential activity for our lab members. Sharing our research work with the public who fund it and the wider world is a crucial part of our mission.
The research group, is very active and participating in a variety of public engagement opportunities, such as School Visits, Café Scientifique, Pint of Science, Science Festivals, Researcher in Residence Programme, University Open Days, and by organising fundraising events, public lectures and workshops.
Our Research Lab is consistently publishing in high quality top quartile internationally recognised journals including the Mater. Sci. Eng. C Mater. Biol. Appl. (IF: 8.457), ACS Appl. Mater Interf. (IF 9.441), Acta Biomaterialia (IF 10.633), Chem (IF 25.832) and Nature Nanotechnology (IF 40.523).
Selected publications from our Lab in 3D Printing, 4D Printing, and Bioprinting:
Machine Learning in Additive Manufacturing & Microfluidics for Smarter and Safer Drug Delivery Systems
Combining 3D printing and microfluidic techniques: a powerful synergy for nanomedicine
3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma
In-house Innovative ‘Diamond Shaped’ 3D Printed Microfluidic Devices for Lysozyme-Loaded Liposomes
3D Printed Biodegradable Multifunctional Implants for Effective Breast Cancer Treatment
3D-printed Microfluidic Chips to Analyse the Effect Upon Particle Size During the Synthesis of Lipid Nanoparticles
3D Bioprinted Chitosan-Based Hydrogel Scaffolds in Tissue Engineering and Localised Drug Delivery
3D printing in Ophthalmology: From medical implants to personalised medicine
The sustainability of emerging technologies for use in pharmaceutical manufacturing
Stereolithography 3D Printed Implants: A Preliminary Investigation as Potential Local Drug Delivery Systems to the Ear
3D bioprinted scaffolds for diabetic wound healing applications
Optimization of Printing Parameters for Digital Light Processing 3D Printing of Hollow Microneedle Arrays
Melt-extrusion 3DP of resorbable levofloxacin-loaded meshes: emerging strategy for Urogynaecological applications
Fused deposition modeling 3D printing proof-of-concept study for personalised inner ear therapy
Optimization of FDM 3D Printing process parameters to produce haemodialysis curcumin-loaded vascular grafts
3D Printing: an appealing technology for the manufacturing of Solid Oral Dosage Forms
Development of drug loaded cardiovascular prosthesis for thrombosis prevention using 3D printing
Manufacturing of 3D-printed microfluidic devices for the synthesis of drug-loaded liposomal formulations
3D Scaffolds in the Treatment of Diabetic Foot Ulcers: New Trends vs Conventional Approaches
Antimicrobial 3D printed objects in the fight against pandemics
Fused deposition modelling for the development of drug loaded cardiovascular prosthesis
Next generation surgical meshes for drug delivery & tissue engineering applications: materials, design & emerging technologies
3D printed estradiol-eluting urogynecological mesh Implants: Influence of material & mesh geometry on their mechanical properties
Long-acting implantable devices for prevention & personalised treatment of infectious, inflammatory & chronic diseases
PCL-based coatings on 3D printed biodegradable implants: A novel strategy to prolong delivery of hydrophilic drugs
Urogynecological surgical mesh implants: new trends in materials, manufacturing and therapeutic approaches
Additive Manufacturing can assist in the fight against COVID-19 & other pandemics & impact on the global supply chain
Development of a biodegradable sub-cutaneous implant for prolonged drug delivery using 3D printing
3D printing of drug-loaded TPU meshes: A potential material for soft tissue reinforcement in vaginal surgery
Fused Deposition Modeling as an Effective Tool for Anti-Infective Dialysis Catheter Fabrication
FDM as a Potential Tool for Antimicrobial Dialysis Catheters Manufacturing: New Trends vs. Conventional Approaches
3D printed microneedle patches using stereolithography (SLA) for intradermal insulin delivery
PubMed-based algorithms placed us in the top 0.088% of scholars in the world writing about 3D Printing
Books edited by our Lab in 3D Printing, Bioprinting, and 4D Printing!
3D Printing of Pharmaceutical and Drug Delivery Devices: Progress from Bench to Bedside
The book offers a comprehensive overview of 3D printing technology and its pharmaceutical applications. It introduces readers to a world in which bespoke drug delivery systems developed for specific users or conditions is rapidly becoming a reality.
3D & 4D Printing Methods for Pharmaceutical Manufacturing and Personalised Drug Delivery: Opportunities & Challenges.
The book is covering the basics behind each additive manufacturing (AM) method, current applications in pharmaceutics for each 3DP method, and case studies (examples) from a teaching perspective, targeting undergraduate (UG) and postgraduate (PG) students.
SUPPORT US / SPONSORSHIP
We are grateful to our generous sponsors!
The major aim of our lab is to develop innovative 3D Printing, 4D Printing, and Bioprinting approaches for a variety of applications as well as training next generation's talented students and postdocs.
One of the most direct ways of contributing to these causes is by donating towards a research aim or sponsoring any of our group members directly. If you would like to donate to our research, please contact us for further information.
Lamprou Lab, Queen’s University Belfast, Belfast, United Kingdom